INT1275

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Context Info
Confidence 0.75
First Reported 1976
Last Reported 2004
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 2.92
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (AKR1C2) cytoplasm (AKR1C2)
Anatomy Link Frequency
mammary gland 1
AKR1C2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 81.04 Quite High
headache 1 80.32 Quite High
corticosteroid 10 13.12 Low Low
Analgesic 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis 4 100.00 Very High Very High Very High
Reprotox - General 1 5 99.84 Very High Very High Very High
Breast Cancer 115 98.16 Very High Very High Very High
Cytomegalovirus Infection 8 91.68 High High
Hepatotoxicity 3 90.12 High High
Cancer 340 89.40 High High
Infection 3 86.16 High High
Disease 2 85.40 High High
Fatigue 1 82.48 Quite High
Myalgia 1 81.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-HSO3 (AKR1C2) expression in tumorous than in the paired nontumorous tissue.
Gene_expression (expression) of AKR1C2
1) Confidence 0.75 Published 2004 Journal BMC Cancer Section Body Doc Link PMC459223 Disease Relevance 0.40 Pain Relevance 0
The expression of AKR1C1, AKR1C2 and AKR1C3 mRNAs has been detected in human mammary gland [24,27-29].
Gene_expression (expression) of AKR1C2 in mammary gland
2) Confidence 0.65 Published 2004 Journal BMC Cancer Section Body Doc Link PMC459223 Disease Relevance 0.11 Pain Relevance 0
-HSO) activity, AKR1C2 has predominantly 3?
Gene_expression (has) of AKR1C2
3) Confidence 0.65 Published 2004 Journal BMC Cancer Section Body Doc Link PMC459223 Disease Relevance 0.11 Pain Relevance 0
Thus reduced expression of AKR1C2 in prostate cancer has been considered to be associated with reduced conversion of 5?
Gene_expression (expression) of AKR1C2 associated with reprotox - general 1
4) Confidence 0.58 Published 2004 Journal BMC Cancer Section Body Doc Link PMC459223 Disease Relevance 0.41 Pain Relevance 0
Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma

Background

Gene_expression (Expression) of AKR1C2 associated with breast cancer
5) Confidence 0.58 Published 2004 Journal BMC Cancer Section Title Doc Link PMC459223 Disease Relevance 0.32 Pain Relevance 0
Serum hepatitis was initially suspected in both cases, but repeated examinations of the sera revealed no hepatitis B antigen or antibodies (HbAg and HbAb).
Neg (no) Spec (examinations) Gene_expression (revealed) of HbAb associated with hepatitis
6) Confidence 0.57 Published 1976 Journal Int Urol Nephrol Section Abstract Doc Link 184060 Disease Relevance 1.58 Pain Relevance 0.16

General Comments

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