INT127648

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Context Info
Confidence 0.13
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.11
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Wnt7a) extracellular space (Wnt7a) extracellular region (Wnt7a)
proteinaceous extracellular matrix (Wnt7a) plasma membrane (Wnt7a) cell-cell signaling (Wnt7a)
Wnt7a (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 3 86.56 High High
Pain score 1 84.32 Quite High
COX-2 inhibitor 1 72.40 Quite High
Pain 2 69.44 Quite High
cINOD 2 67.24 Quite High
anesthesia 1 52.84 Quite High
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 8 91.52 High High
Disorder Of Lipid Metabolism 5 88.20 High High
Osteoarthritis 1 86.56 High High
Pain 3 84.32 Quite High
Knee Osteoarthritis 2 82.88 Quite High
Stress 2 73.92 Quite High
INFLAMMATION 1 66.68 Quite High
Body Weight 1 44.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activities of antioxidant enzymes (CAT and GSH-Px) and GSH level in hepatic, pancreatic and renal tissues also increased significantly (P < 0.05) in BMEE-treated mice, but the activity of SOD was not improved significantly.
Gene_expression (level) of GSH-Px
1) Confidence 0.13 Published 2009 Journal Indian J. Biochem. Biophys. Section Abstract Doc Link 19374261 Disease Relevance 0.51 Pain Relevance 0.05
Tenoxicam-treated patients had significant decrease in nitrite levels (p = 0.036) and XO activity (p = 0.01), but their SOD, GSH-Px enzyme activities, and MDA levels were unchanged from baseline.
Gene_expression (activities) of GSH-Px enzyme
2) Confidence 0.10 Published 2005 Journal Ann. Clin. Lab. Sci. Section Abstract Doc Link 15943176 Disease Relevance 0.60 Pain Relevance 0.51

General Comments

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