INT12766

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Context Info
Confidence 0.53
First Reported 1991
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.07
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ins1, Prkcg) intracellular (Prkcg) carbohydrate metabolic process (Ins1)
response to stress (Prkcg) cytosol (Prkcg) extracellular space (Ins1)
Anatomy Link Frequency
neurons 1
skeletal muscle 1
Ins1 (Rattus norvegicus)
Prkcg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 13 100.00 Very High Very High Very High
Hippocampus 8 88.08 High High
tetrodotoxin 3 85.96 High High
Pyramidal cell 4 74.32 Quite High
antagonist 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 1 72.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, insulin can stimulate PKC activity in cultured fetal chick neurons.
insulin Positive_regulation (stimulate) of PKC in neurons associated with kinase c
1) Confidence 0.53 Published 1991 Journal Brain Res. Section Abstract Doc Link 1653632 Disease Relevance 0 Pain Relevance 0.31
Insulin stimulates membrane phospholipid metabolism and activates protein kinase C (PKC) in its peripheral target tissues.
Insulin Positive_regulation (activates) of PKC associated with kinase c
2) Confidence 0.53 Published 1991 Journal Brain Res. Section Abstract Doc Link 1653632 Disease Relevance 0 Pain Relevance 0.30
The findings suggest that insulin may stimulate Na(+)-K+ pump activity in skeletal muscle by activation of PKC.
insulin Positive_regulation (activation) of PKC in skeletal muscle associated with kinase c
3) Confidence 0.36 Published 1994 Journal Am. J. Physiol. Section Abstract Doc Link 8166238 Disease Relevance 0.07 Pain Relevance 0.29

General Comments

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