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Context Info
Confidence 0.14
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6, PDE4A) nucleus (IRF6, PDE4A) cytoplasm (IRF6, PDE4A)
signal transduction (PDE4A) plasma membrane (PDE4A) DNA binding (IRF6)
IRF6 (Homo sapiens)
PDE4A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 93.72 High High
Inflammatory response 3 86.84 High High
cytokine 3 86.40 High High
metalloproteinase 2 82.68 Quite High
Dismenorea 1 81.44 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 93.72 High High
Dysmenorrhea 1 81.44 Quite High
Bacterial Infection 1 74.12 Quite High
Premature Rupture Fetal Membranes 1 72.44 Quite High
Infection 3 69.76 Quite High
Rupture 2 68.40 Quite High
Premature Birth 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that PDE4 family is the major cAMP-PDE expressed in human fetal membranes and that PDE4 activity is increased by LPS treatment.
LPS Positive_regulation (increased) of PDE4
1) Confidence 0.14 Published 2005 Journal J. Immunol. Section Abstract Doc Link 15944316 Disease Relevance 0.76 Pain Relevance 0.48

General Comments

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