INT127670

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Context Info
Confidence 0.54
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 1.75
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lysosome (ARSD)
Anatomy Link Frequency
external 1
eye field 1
ARSD (Homo sapiens)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 249 100.00 Very High Very High Very High
depression 8 95.76 Very High Very High Very High
Osteoarthritis 49 94.28 High High
Inflammation 18 92.92 High High
rheumatoid arthritis 68 91.76 High High
Neuropeptide 11 77.36 Quite High
imagery 75 76.88 Quite High
Anterior cingulate 3 75.00 Quite High
cINOD 6 64.88 Quite High
Leflunomide 5 64.16 Quite High
Disease Link Frequency Relevance Heat
Genetic Predisposition To Disease 1 96.88 Very High Very High Very High
Depression 8 95.76 Very High Very High Very High
Frailty 50 94.28 High High
INFLAMMATION 18 92.92 High High
Rheumatoid Arthritis 68 91.76 High High
Congenital Anomalies 43 86.80 High High
Autism 92 82.60 Quite High
Traumatic Stress Disorders 1 75.52 Quite High
Post-traumatic Stress Disorder 1 74.24 Quite High
Asperger Syndrome 5 72.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regions of greater activation in controls are depicted in warm colours; greater activation in ASD patients is depicted in blue.
Positive_regulation (activation) of ASD
1) Confidence 0.54 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0 Pain Relevance 0.03
Rather unexpected are the low scores on the „physical health“ domain, as physical impairment is no key component of ASD.
Positive_regulation (component) of ASD
2) Confidence 0.43 Published 2010 Journal GMS Psycho-Social-Medicine Section Body Doc Link PMC2940215 Disease Relevance 0.17 Pain Relevance 0.05
All patients underwent standard ASD.
Positive_regulation (underwent) of ASD
3) Confidence 0.39 Published 2005 Journal Arthroscopy Section Body Doc Link 15944622 Disease Relevance 0 Pain Relevance 0
Thus, in ASD, aberrant communication between response evaluation in the ACC and regions initiating compensatory adjustments, possibly lateral prefrontal cortex, could result in a failure to optimally reduce preparatory firing rates in frontal eye field in response to a prior error.
Positive_regulation (result) of ASD in eye field associated with anterior cingulate cortex
4) Confidence 0.36 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0 Pain Relevance 0.13
Finally, in ASD (v) increased activation on correct trials and reduced FA in rACC WM were related to higher ratings of repetitive behaviour.
Positive_regulation (increased) of ASD
5) Confidence 0.36 Published 2008 Journal Brain Section Abstract Doc Link PMC2525446 Disease Relevance 0.43 Pain Relevance 0.44
However, our working hypothesis is that ASD can be caused or influenced by external events in early childhood, possibly as result of a genetic predisposition.
Positive_regulation (caused) of ASD in external associated with genetic predisposition to disease
6) Confidence 0.35 Published 2005 Journal BMC Psychiatry Section Body Doc Link PMC1190193 Disease Relevance 0.46 Pain Relevance 0.23
DHEA is the major delta 5 androgen (Fig. 1), which is converted to androstenediol, ASD, 16?
Positive_regulation (converted) of ASD
7) Confidence 0.25 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257423 Disease Relevance 0.69 Pain Relevance 0.44
CONCLUSIONS: In this small study, both dexmedetomidine and ketamine in combination with propofol were well tolerated in these pediatric patients who required ASD closure.
Positive_regulation (required) of ASD
8) Confidence 0.04 Published 2010 Journal Clin Ther Section Body Doc Link 20435239 Disease Relevance 0 Pain Relevance 0

General Comments

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