INT127672

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Context Info
Confidence 0.17
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.28
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NGFR, NTRK1) endosome (NGFR, NTRK1) plasma membrane (NGFR, NTRK1)
nucleoplasm (NGFR) cytoplasm (NGFR) signal transducer activity (NGFR)
NGFR (Homo sapiens)
NTRK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
backache 2 99.24 Very High Very High Very High
Pain 4 97.80 Very High Very High Very High
Nerve growth factor 16 97.28 Very High Very High Very High
Disease Link Frequency Relevance Heat
Low Back Pain 2 99.24 Very High Very High Very High
Pain 4 97.80 Very High Very High Very High
Pancreatic Cancer 16 96.00 Very High Very High Very High
Cancer 10 94.72 High High
Aggression 2 73.52 Quite High
Breast Cancer 2 71.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For Cox univariate analyses in the OS study, high expression of p75NGFR was associated with longer overall survival yet TrkA exhibited opposite effects and included the effect of pain.
p75NGFR Binding (associated) of TrkA associated with pain
1) Confidence 0.17 Published 2005 Journal Oncol. Rep. Section Abstract Doc Link 15944784 Disease Relevance 1.17 Pain Relevance 0.46
TrkA and p75NGFR negatively correlated and were both associated with abdominal or back pain and perineural invasion.
p75NGFR Binding (associated) of TrkA associated with backache
2) Confidence 0.17 Published 2005 Journal Oncol. Rep. Section Abstract Doc Link 15944784 Disease Relevance 1.11 Pain Relevance 0.51

General Comments

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