INT127673

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Context Info
Confidence 0.48
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.12
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (NGF, NTRK1) cell differentiation (NTRK1) signal transduction (NGF)
extracellular space (NGF) extracellular region (NGF) plasma membrane (NTRK1)
NGF (Homo sapiens)
NTRK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 16 100.00 Very High Very High Very High
backache 2 92.32 High High
Pain 4 80.64 Quite High
Disease Link Frequency Relevance Heat
Pancreatic Cancer 16 100.00 Very High Very High Very High
Cancer 10 96.32 Very High Very High Very High
Low Back Pain 2 92.32 High High
Breast Cancer 2 84.68 Quite High
Pain 4 80.64 Quite High
Aggression 2 39.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It appears that in pancreatic cancer cells the growth effects of NGF depend on the expression levels and the ratio of TrkA and p75NGFR.
NGF Regulation (depend) of Gene_expression (expression) of TrkA associated with nerve growth factor and pancreatic cancer
1) Confidence 0.48 Published 2005 Journal Oncol. Rep. Section Abstract Doc Link 15944784 Disease Relevance 1.11 Pain Relevance 0.50
Moreover, pancreatic cancer cell lines were used to validate if the effects of NGF on pancreatic cancer cell growth are dependent on the expression levels and the balance of TrkA and P75 receptors.
NGF Regulation (dependent) of Gene_expression (expression) of TrkA associated with nerve growth factor and pancreatic cancer
2) Confidence 0.48 Published 2005 Journal Oncol. Rep. Section Abstract Doc Link 15944784 Disease Relevance 1.01 Pain Relevance 0.42

General Comments

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