INT127726

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Context Info
Confidence 0.10
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (CSF1) cell proliferation (CSF1) extracellular space (CSF1)
extracellular region (CSF1) plasma membrane (CSF1)
Anatomy Link Frequency
macrophage 2
CSF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 62.12 Quite High
Disease Link Frequency Relevance Heat
Metastasis 2 75.00 Quite High
Breast Cancer 2 68.76 Quite High
Pain 1 62.12 Quite High
Bone Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment of HDS cells with gefitinib produced a significant reduction in the levels of secreted macrophage colony-stimulating factor (M-CSF) and cell-associated receptor activator of NF-kappaB ligand (RANKL) in both cell lines, as assessed by using specific ELISA and Western blotting techniques.
Negative_regulation (reduction) of Localization (secreted) of M-CSF in macrophage
1) Confidence 0.10 Published 2005 Journal Endocr. Relat. Cancer Section Abstract Doc Link 15947117 Disease Relevance 0.27 Pain Relevance 0.06

General Comments

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