INT127961

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 4.34
Pain Relevance 8.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (GRHL3) DNA binding (GRHL3)
Anatomy Link Frequency
sciatic nerve 2
dorsal horn 1
GRHL3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 40 100.00 Very High Very High Very High
electroacupuncture 35 99.84 Very High Very High Very High
dorsal root ganglion 15 99.84 Very High Very High Very High
spinal dorsal horn 10 99.76 Very High Very High Very High
Neuropathic pain 25 99.56 Very High Very High Very High
Eae 15 99.36 Very High Very High Very High
Sciatic nerve 5 98.24 Very High Very High Very High
Analgesic 5 90.56 High High
Neuropeptide 5 89.80 High High
Opioid 5 89.28 High High
Disease Link Frequency Relevance Heat
Ganglion Cysts 20 99.84 Very High Very High Very High
Neuropathic Pain 25 99.56 Very High Very High Very High
Injury 15 99.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using immunohistochemistry and RT-PCR, the present study observed the effects of EA on the expression of SOM peptide and preprosomatostatin (ppSOM) mRNA in a rat model of neuropathic pain induced by chronic constriction injury (CCI) to the sciatic nerve.
Transcription (expression) of SOM in sciatic nerve associated with eae, injury, neuropathic pain, somatostatin, sciatic nerve and electroacupuncture
1) Confidence 0.45 Published 2005 Journal Neurosci. Lett. Section Abstract Doc Link 15970377 Disease Relevance 0.81 Pain Relevance 1.57
Using immunohistochemistry and RT-PCR, the present study observed the effects of EA on the expression of SOM peptide and preprosomatostatin (ppSOM) mRNA in a rat model of neuropathic pain induced by chronic constriction injury (CCI) to the sciatic nerve.
Transcription (expression) of ppSOM in sciatic nerve associated with eae, injury, neuropathic pain, somatostatin, sciatic nerve and electroacupuncture
2) Confidence 0.39 Published 2005 Journal Neurosci. Lett. Section Abstract Doc Link 15970377 Disease Relevance 0.83 Pain Relevance 1.60
No significant change was detected in the expression of SOM and ppSOM mRNA following CCI.
Transcription (expression) of ppSOM associated with eae and somatostatin
3) Confidence 0.34 Published 2005 Journal Neurosci. Lett. Section Abstract Doc Link 15970377 Disease Relevance 0.90 Pain Relevance 1.67
No significant change was detected in the expression of SOM and ppSOM mRNA following CCI.
Transcription (expression) of SOM associated with eae and somatostatin
4) Confidence 0.34 Published 2005 Journal Neurosci. Lett. Section Abstract Doc Link 15970377 Disease Relevance 0.89 Pain Relevance 1.66
However, EA could significantly enhance SOM expression in dorsal root ganglion (DRG) and spinal dorsal horn as well as ppSOM mRNA level in DRG of neuropathic pain rats.
Transcription (level) of ppSOM in dorsal horn associated with ganglion cysts, dorsal root ganglion, spinal dorsal horn, neuropathic pain, somatostatin and electroacupuncture
5) Confidence 0.34 Published 2005 Journal Neurosci. Lett. Section Abstract Doc Link 15970377 Disease Relevance 0.91 Pain Relevance 1.68

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