INT127970

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2004
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.24

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small molecule metabolic process (HEXB) cell death (HEXB) carbohydrate metabolic process (HEXB)
lysosome (HEXB)
Anatomy Link Frequency
reticulum 1
HEXB (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 5 84.52 Quite High
depression 1 35.60 Quite Low
Disease Link Frequency Relevance Heat
Migraine With Aura 3 84.92 Quite High
Headache 2 41.36 Quite Low
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Metabolic labeling studies showed that the mutants were synthesized and associated with the beta-subunit, except for the alpha2HW887R mutant, which was poorly synthesized, and the alpha1BW890R, which was partially retained in the endoplasmic reticulum. [3H]ouabain binding showed the presence of the alpha2HR689Q and alpha2HM731T at the membrane, whereas the alpha2HL764P and alpha2HW887R could not be detected.
beta-subunit Neg (except) Binding (associated) of in reticulum
1) Confidence 0.01 Published 2004 Journal Neuromolecular Med. Section Abstract Doc Link 15970628 Disease Relevance 0.24 Pain Relevance 0.24

General Comments

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