INT128085

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.46
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCC1) small molecule metabolic process (ABCC1) Golgi apparatus (ABCC1)
nucleolus (ABCC1) ATPase activity (ABCC1) plasma membrane (ABCC1)
Anatomy Link Frequency
liver 2
ABCC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 87.12 High High
dexamethasone 1 52.24 Quite High
Morphine 3 50.00 Quite Low
Inflammation 1 25.00 Low Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gallstones 2 92.44 High High
INFLAMMATION 2 86.72 High High
Asthma 1 81.52 Quite High
Lung Cancer 3 80.88 Quite High
Cancer 1 59.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Multidrug resistance proteins, which catalyse the detoxification of xenobiotics and excretion of metabolites, are very often controlled at the transcriptional level by interaction of exogenous compounds or hormones with nuclear receptors.
Regulation (controlled) of Transcription (at) of Multidrug resistance
1) Confidence 0.06 Published 2005 Journal J. Steroid Biochem. Mol. Biol. Section Abstract Doc Link 15979871 Disease Relevance 0.37 Pain Relevance 0.11
Changes in the mRNA expression of multidrug resistance-associated protein (MRP)2, MRP3 and UDP-glucuronosyltransferase (UGT)2B1 in the liver were estimated using RT-PCR.
Regulation (Changes) of Transcription (expression) of multidrug resistance-associated protein in liver
2) Confidence 0.02 Published 2009 Journal J. Pharm. Pharmacol. Section Body Doc Link 19703370 Disease Relevance 0.09 Pain Relevance 0

General Comments

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