INT128237

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Context Info
Confidence 0.07
First Reported 2003
Last Reported 2005
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Adam32 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 2 97.52 Very High Very High Very High
antagonist 1 97.26 Very High Very High Very High
narcan 1 96.96 Very High Very High Very High
Morphine 8 96.04 Very High Very High Very High
Paracetamol 1 90.88 High High
orphanin 4 75.00 Quite High
Inflammation 3 67.68 Quite High
cytokine 5 50.96 Quite High
Inflammatory response 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 14 95.84 Very High Very High Very High
Cancer 3 90.88 High High
Necrosis 4 90.40 High High
Fatty Liver 1 74.44 Quite High
Poisoning 1 71.08 Quite High
INFLAMMATION 4 67.68 Quite High
Injury 6 60.08 Quite High
Hyperplasia 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Exsanguination 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The morphine-induced enhancement was abolished by naloxone, an antagonist of mu opioid peptide receptor (MOP), wortmannin, a phosphoinositide 3-kinase (PI3K) inhibitor, and PD98059, a MEK inhibitor, but not by 1,10-phenanthroline, a metalloprotease inhibitor and U73122, a phospholipase C inhibitor.
Neg (not) Gene_expression (1,10-phenanthroline) of metalloprotease associated with antagonist, narcan, opioid and morphine
1) Confidence 0.07 Published 2005 Journal Peptides Section Abstract Doc Link 15990199 Disease Relevance 0 Pain Relevance 1.03
Expression of distintegrin metalloprotease (Z48444) was positively correlated with the two vacuole-related metrics.
Gene_expression (Expression) of distintegrin metalloprotease
2) Confidence 0.01 Published 2003 Journal Genome Biol Section Body Doc Link PMC156588 Disease Relevance 0.64 Pain Relevance 0.15

General Comments

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