INT128254

Context Info Confidence 0.04 First Reported 1994 Last Reported 2005 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.78 Pain Relevance 0.71

Hdlcl1 (Mus musculus)

Pain Link Frequency Relevance Heat fluoxetine 7 99.24 Glutamate 1 79.20 Analgesic 1 73.72 Inflammation 2 73.28

Disease Link Frequency Relevance Heat Disorder Of Lipid Metabolism 5 100.00 Weight Loss 2 87.88 Metabolic Syndrome 1 75.00 Arthritis 1 74.36 Overweight 2 73.68 INFLAMMATION 1 73.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Under in vivo experiment, BS extract significantly reduced serum total cholesterol (38-48 %), increased serum high-density lipoprotein- cholesterol (HDL-cholesterol, 22-30%).

Negative_regulation (reduced) of Positive_regulation (increased) of HDL-cholesterol associated with disorder of lipid metabolism

1) Confidence 0.04 Published 2005 Journal Indian J. Exp. Biol. Section Abstract Doc Link 15991575 Disease Relevance 0.35 Pain Relevance 0.15

A reduction of serum triglycerides and an increase of HDL-cholesterol were found in the fluoxetine treated group.

Negative_regulation (reduction) of Positive_regulation (increase) of HDL-cholesterol associated with disorder of lipid metabolism and fluoxetine

2) Confidence 0.02 Published 1994 Journal Obes. Res. Section Abstract Doc Link 16353616 Disease Relevance 0.43 Pain Relevance 0.56

General Comments

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