INT128281

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Context Info
Confidence 0.36
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (JUND, NFKB1) nucleoplasm (NFKB1) mitochondrion (NFKB1)
cytoplasm (NFKB1) cytosol (NFKB1) signal transduction (NFKB1)
JUND (Homo sapiens)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 3 92.72 High High
Bioavailability 1 80.24 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 2 97.96 Very High Very High Very High
Cancer 4 76.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Some of these agents (EGCG, genistein, and curcumin) appear to directly target specific RTKs, and all of these compounds cause inhibition of the activity of the transcription factors AP-1 and NF-kappaB, thus inhibiting cell proliferation and enhancing apoptosis.
AP-1 Binding (activity) of NF-kappaB associated with apoptosis
1) Confidence 0.36 Published 2005 Journal Mutat. Res. Section Abstract Doc Link 15992833 Disease Relevance 0.39 Pain Relevance 0.13

General Comments

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