INT128296

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 1.36
Pain Relevance 4.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B, Insr) endosome (Insr) aging (IL1B)
cell-cell signaling (IL1B) extracellular space (IL1B) signal transduction (IL1B)
Anatomy Link Frequency
parabrachial nucleus 4
neurons 2
area postrema 1
cell groups 1
IL1B (Homo sapiens)
Insr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 16 99.68 Very High Very High Very High
narcan 32 99.10 Very High Very High Very High
Catecholamine 8 98.64 Very High Very High Very High
opioid receptor 28 98.56 Very High Very High Very High
parabrachial 4 96.80 Very High Very High Very High
amygdala 12 90.56 High High
Endogenous opioid 8 80.32 Quite High
cytokine 4 62.52 Quite High
Inflammation 4 62.16 Quite High
Opioid 4 52.24 Quite High
Disease Link Frequency Relevance Heat
Toxocariasis 12 99.68 Very High Very High Very High
INFLAMMATION 4 62.16 Quite High
Infection 4 53.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We next determined the effect of blocking both central and peripheral opioid receptors with naloxone and, when compared to the naloxone methiodide pre-treated group, a further 60% decrease in Fos-IR mPVN CRH neurons induced by IL-1beta was detected, which was attributed to block of central opioid receptors.
Negative_regulation (decrease) of IL-1beta Positive_regulation (induced) of Fos-IR in neurons associated with narcan and opioid receptor
1) Confidence 0.10 Published 2005 Journal Neuropharmacology Section Abstract Doc Link 15993445 Disease Relevance 0.37 Pain Relevance 1.19
Similar comparisons also detected decreases in Fos-IR neurons induced by IL-1beta in the VLM A1, VLM C1 and NTS A2 catecholamine cell groups, area postrema, and parabrachial nucleus.
Negative_regulation (decreases) of IL-1beta Positive_regulation (induced) of Fos-IR in parabrachial nucleus associated with medulla, catecholamine and parabrachial
2) Confidence 0.10 Published 2005 Journal Neuropharmacology Section Abstract Doc Link 15993445 Disease Relevance 0.33 Pain Relevance 1.11
Similar comparisons also detected decreases in Fos-IR neurons induced by IL-1beta in the VLM A1, VLM C1 and NTS A2 catecholamine cell groups, area postrema, and parabrachial nucleus.
Negative_regulation (decreases) of IL-1beta in cell groups Positive_regulation (induced) of Fos-IR in parabrachial nucleus associated with medulla, catecholamine and parabrachial
3) Confidence 0.03 Published 2005 Journal Neuropharmacology Section Abstract Doc Link 15993445 Disease Relevance 0.33 Pain Relevance 1.11
Similar comparisons also detected decreases in Fos-IR neurons induced by IL-1beta in the VLM A1, VLM C1 and NTS A2 catecholamine cell groups, area postrema, and parabrachial nucleus.
Negative_regulation (decreases) of IL-1beta in area postrema Positive_regulation (induced) of Fos-IR in parabrachial nucleus associated with medulla, catecholamine and parabrachial
4) Confidence 0.03 Published 2005 Journal Neuropharmacology Section Abstract Doc Link 15993445 Disease Relevance 0.33 Pain Relevance 1.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox