INT128297

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1b, CRH) extracellular region (Il1b, CRH) signal transduction (CRH)
aging (Il1b) response to stress (CRH)
Anatomy Link Frequency
nucleus 1
Il1b (Rattus norvegicus)
CRH (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 8 99.44 Very High Very High Very High
medulla 4 97.80 Very High Very High Very High
opioid receptor 7 97.04 Very High Very High Very High
Catecholamine 2 95.00 High High
cytokine 1 89.12 High High
Inflammation 1 88.76 High High
Opioid 1 78.84 Quite High
amygdala 3 77.76 Quite High
Endogenous opioid 2 75.00 Quite High
Morphine 1 73.28 Quite High
Disease Link Frequency Relevance Heat
Toxocariasis 3 97.44 Very High Very High Very High
INFLAMMATION 1 88.76 High High
Infection 1 79.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pre-treatment with naloxone methiodide decreased (15%) IL-1beta-induced Fos-immunoreactivity (Fos-IR) in medial parvocellular paraventricular nucleus (mPVN) corticotropin-releasing hormone (CRH) neurons but increased responses in the ventrolateral medulla (VLM) C1 (65%) and nucleus tractus solitarius (NTS) A2 (110%) catecholamine cell groups and area postrema (136%).
IL-1beta-induced Positive_regulation (induced) of CRH in nucleus associated with medulla, catecholamine and narcan
1) Confidence 0.02 Published 2005 Journal Neuropharmacology Section Abstract Doc Link 15993445 Disease Relevance 0.27 Pain Relevance 1.03

General Comments

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