INT128309

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 1.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Tmbim6) cellular_component (Tmbim6)
Tmbim6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Antinociceptive 2 99.28 Very High Very High Very High
Potency 4 98.64 Very High Very High Very High
intrathecal 5 98.20 Very High Very High Very High
Morphine 7 97.72 Very High Very High Very High
withdrawal 1 95.40 Very High Very High Very High
Sciatic nerve 3 90.72 High High
mu opioid receptor 2 75.00 Quite High
antinociception 1 75.00 Quite High
Opioid 1 69.36 Quite High
Lasting pain 1 58.72 Quite High
Disease Link Frequency Relevance Heat
Pain 1 58.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared with rats injected with rAAV containing the enhanced green fluorescent protein gene (rAAV-EGFP), the antinociceptive potency of intrathecal morphine in rAAV-muOR rats was significantly increased, and the effective dose (ED50) for morphine was 5.4-fold lower (rAAV-muOR: ED50 = 0.84 microg, confidence interval, 0.70-0.99 microg; rAAV-EGFP: ED50 = 4.50 microg, confidence interval, 3.55-5.86 microg).
Positive_regulation (enhanced) of rAAV containing the enhanced green fluorescent protein gene associated with antinociceptive, morphine, intrathecal and potency
1) Confidence 0.03 Published 2005 Journal J Pain Section Abstract Doc Link 15993823 Disease Relevance 0.06 Pain Relevance 1.31

General Comments

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