INT128310

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Oprm1, Oprm1) signal transduction (Oprm1) plasma membrane (Oprm1)
Anatomy Link Frequency
nerve 1
Oprm1 (Rattus norvegicus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 4 99.34 Very High Very High Very High
Opioid 1 99.18 Very High Very High Very High
Lasting pain 1 97.56 Very High Very High Very High
Morphine 7 89.00 High High
Sciatic nerve 3 86.80 High High
intrathecal 5 85.04 High High
Antinociceptive 2 84.12 Quite High
withdrawal 1 75.84 Quite High
mu opioid receptor 2 75.00 Quite High
antinociception 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Pain 1 97.56 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With minimum tissue damage and a large persistent increase in the opioid potency, remote nerve injection of rAAV-muOR to up-regulate muORs could be a useful therapeutic strategy for the treatment of chronic pain.
muOR Positive_regulation (up-regulate) of muORs in nerve associated with lasting pain, opioid and potency
1) Confidence 0.00 Published 2005 Journal J Pain Section Abstract Doc Link 15993823 Disease Relevance 0.10 Pain Relevance 1.29

General Comments

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