INT128323

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.21
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Per3) nucleus (Per3) cytoplasm (Per3)
signal transducer activity (Per3)
Anatomy Link Frequency
neuronal 2
livers 2
Per3 (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 4 100.00 Very High Very High Very High
cocaine 4 100.00 Very High Very High Very High
antidepressant 2 100.00 Very High Very High Very High
Serotonin 2 95.16 Very High Very High Very High
addiction 1 92.08 High High
agonist 8 89.32 High High
Hippocampus 3 81.76 Quite High
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 1 92.08 High High
Metabolic Syndrome 8 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Sleep Disorders 3 5.00 Very Low Very Low Very Low
Repression 3 5.00 Very Low Very Low Very Low
Obesity 3 5.00 Very Low Very Low Very Low
Thinness 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Dyslipidemia /

Combined Dyslipidemia

1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Changes in Bmal1 and Per3 expression was observed in the livers of PPAR?
Regulation (Changes) of Gene_expression (expression) of Per3 in livers
1) Confidence 0.21 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943104 Disease Relevance 0 Pain Relevance 0.04
In this study in mice, we investigated the delayed effects of single and repeated (i.e. 14 days) administration of the antidepressant fluoxetine and the psychostimulant cocaine on the brain expression of clock genes Period1, Period2, Period3, Clock, Bmal1, Cryptochrome1, Cryptochrome2, and NPAS2 (neuronal PAS domain protein 2), and their putative target gene, serotonin N-acetyltransferase.
Spec (investigated) Regulation (effects) of Gene_expression (expression) of Period3 in neuronal associated with antidepressant, serotonin, cocaine and fluoxetine
2) Confidence 0.04 Published 2005 Journal Neuroscience Section Abstract Doc Link 15994025 Disease Relevance 0.09 Pain Relevance 0.65

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox