INT128431

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.48
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 0.65
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SLC6A4) endosome (SLC6A4) nucleus (S100A4)
plasma membrane (SLC6A4)
SLC6A4 (Homo sapiens)
S100A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 6 100.00 Very High Very High Very High
monoamine 4 87.88 High High
fluoxetine 2 76.48 Quite High
antagonist 2 75.56 Quite High
Disease Link Frequency Relevance Heat
Hypertension 4 99.18 Very High Very High Very High
Increased Venous Pressure Under Development 6 98.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data provide evidence for a mechanistic link between the 5-HT pathway and S100A4/Mts1 in pulmonary hypertension and explain how the 5-HT1B receptor and SERT are codependent in regulating S100A4/Mts1.
SERT Regulation (regulating) of S100A4 associated with hypertension
1) Confidence 0.48 Published 2005 Journal Circ. Res. Section Abstract Doc Link 16002749 Disease Relevance 0.28 Pain Relevance 0.24
Interdependent serotonin transporter and receptor pathways regulate S100A4/Mts1, a gene associated with pulmonary vascular disease.
serotonin transporter Regulation (regulate) of S100A4 associated with increased venous pressure under development and serotonin
2) Confidence 0.48 Published 2005 Journal Circ. Res. Section Title Doc Link 16002749 Disease Relevance 0.37 Pain Relevance 0.29

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox