INT128700

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Context Info
Confidence 0.47
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (BBS9, Il12a) cilium (BBS9) microtubule organizing center (BBS9)
extracellular space (Il12a) extracellular region (Il12a) nucleolus (BBS9)
Anatomy Link Frequency
paw 1
BBS9 (Homo sapiens)
Il12a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 2 100.00 Very High Very High Very High
Hyperalgesia 8 99.96 Very High Very High Very High
Morphine 1 98.28 Very High Very High Very High
dexamethasone 1 97.80 Very High Very High Very High
Thermal hyperalgesia 1 75.88 Quite High
cytokine 3 69.68 Quite High
Pain 3 53.84 Quite High
Inflammation 1 49.36 Quite Low
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 10 99.96 Very High Very High Very High
Nociception 1 75.00 Quite High
INFLAMMATION 1 49.36 Quite Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, dexamethasone (2 mg kg(-1)), morphine (3-12 microg paw(-1)), and N-cys-2,6 dimethylpiperidinocarbonyl-L-gamma-methylleucyl-D-1-methoxycarboyl-d-norleucine (BQ788) (ET(B) receptor antagonist; 3-30 nmol paw(-1)) did inhibit IL-12 hyperalgesia.
D-1 Negative_regulation (inhibit) of IL-12 in paw associated with hyperalgesia, antagonist, dexamethasone and morphine
1) Confidence 0.47 Published 2005 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 16024732 Disease Relevance 0.76 Pain Relevance 1.03

General Comments

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