INT128728

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Context Info
Confidence 0.80
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Npy2r) plasma membrane (Npy2r) signal transducer activity (Npy2r)
Anatomy Link Frequency
spinal cord 2
colon 1
jejunum 1
Npy2r (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 10 100.00 Very High Very High Very High
Spinal cord 4 97.52 Very High Very High Very High
Calcitonin gene-related peptide 2 75.52 Quite High
Dorsal horn 4 68.40 Quite High
antagonist 30 61.44 Quite High
agonist 10 55.04 Quite High
dorsal rhizotomy 2 54.32 Quite High
Pain 2 25.00 Low Low
tetrodotoxin 4 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 10 42.32 Quite Low
Nociception 2 25.00 Low Low
Body Weight 2 9.04 Low Low
Pain 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Hyperinsulinism 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The localization of the neuropeptide tyrosine (NPY) Y2 receptor (Y2R) protein was studied in mouse dorsal root ganglia (DRGs) and spinal cord, by using a recently developed rabbit anti-Y2R antibody and a sensitive immunohistochemical method.
Localization (localization) of Y2R in spinal cord associated with neuropeptide and spinal cord
1) Confidence 0.80 Published 2005 Journal J. Comp. Neurol. Section Abstract Doc Link 16025447 Disease Relevance 0 Pain Relevance 0.27
The localization of the neuropeptide tyrosine (NPY) Y2 receptor (Y2R) protein was studied in mouse dorsal root ganglia (DRGs) and spinal cord, by using a recently developed rabbit anti-Y2R antibody and a sensitive immunohistochemical method.
Localization (localization) of Y2 receptor in spinal cord associated with neuropeptide and spinal cord
2) Confidence 0.70 Published 2005 Journal J. Comp. Neurol. Section Abstract Doc Link 16025447 Disease Relevance 0 Pain Relevance 0.27
In rat jejunum and colon Y2 expression occurs in epithelial and muscle layers [28] but as yet no immunohistochemical Y2-receptor localization in the intestine has been described.
Localization (localization) of Y2 in jejunum
3) Confidence 0.12 Published 2008 Journal Nutrition Section Body Doc Link PMC2572019 Disease Relevance 0 Pain Relevance 0.06
In rat jejunum and colon Y2 expression occurs in epithelial and muscle layers [28] but as yet no immunohistochemical Y2-receptor localization in the intestine has been described.
Localization (localization) of Y2 in colon
4) Confidence 0.04 Published 2008 Journal Nutrition Section Body Doc Link PMC2572019 Disease Relevance 0 Pain Relevance 0.06

General Comments

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