INT128812

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Context Info
Confidence 0.19
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk8, Nos2) cytosol (Mapk8, Nos2) signal transduction (Mapk8, Nos2)
nucleus (Mapk8, Nos2) mitochondrion (Mapk8) aging (Nos2)
Anatomy Link Frequency
spinal cord 2
Mapk8 (Rattus norvegicus)
Nos2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 6 99.68 Very High Very High Very High
Thermal hyperalgesia 4 98.88 Very High Very High Very High
Spinal sensitization 1 91.92 High High
intrathecal 3 82.12 Quite High
Dorsal horn 1 61.28 Quite High
withdrawal 1 56.00 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 4 98.88 Very High Very High Very High
Nociception 3 86.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, both ERK and JNK inhibitor pretreatments only partially (approximately 50%) inhibited the IL-1beta-induced iNOS expression in the spinal cord.
JNK Negative_regulation (inhibited) of Gene_expression (expression) of iNOS in spinal cord associated with spinal cord
1) Confidence 0.19 Published 2005 Journal J. Neurochem. Section Abstract Doc Link 16033422 Disease Relevance 0.37 Pain Relevance 0.61

General Comments

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