INT128813

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Context Info
Confidence 0.23
First Reported 2005
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk8, Nos2) cytosol (Mapk8, Nos2) signal transduction (Mapk8, Nos2)
nucleus (Mapk8, Nos2) mitochondrion (Mapk8) aging (Nos2)
Anatomy Link Frequency
spinal cord 2
Mapk8 (Rattus norvegicus)
Nos2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 6 99.68 Very High Very High Very High
intrathecal 3 99.02 Very High Very High Very High
Thermal hyperalgesia 4 80.24 Quite High
Dorsal horn 1 77.20 Quite High
withdrawal 1 71.92 Quite High
Spinal sensitization 1 59.60 Quite High
Disease Link Frequency Relevance Heat
Nociception 3 100.00 Very High Very High Very High
Hyperalgesia 4 80.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intrathecal administration of either selective p38 MAPK, or JNK, or ERK inhibitor alone did not affect the thermal nociceptive threshold or iNOS protein expression in the spinal cord.
JNK Neg (not) Regulation (affect) of Gene_expression (expression) of iNOS protein in spinal cord associated with nociception, spinal cord and intrathecal
1) Confidence 0.23 Published 2005 Journal J. Neurochem. Section Abstract Doc Link 16033422 Disease Relevance 0.46 Pain Relevance 0.74

General Comments

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