INT12895

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Context Info
Confidence 0.14
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 1.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Pdia4) endoplasmic reticulum (Pdia4)
Anatomy Link Frequency
myocytes 2
cardiomyocytes 2
Pdia4 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 11 100.00 Very High Very High Very High
agonist 2 99.26 Very High Very High Very High
opioid receptor 2 99.10 Very High Very High Very High
narcan 6 94.88 High High
Opioid 1 94.64 High High
antagonist 1 94.08 High High
Enkephalin 7 90.52 High High
MU agonist 1 80.96 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment with morphine also abolished the morphine-induced increase in Cai of isolated myocytes.
Negative_regulation (abolished) of Positive_regulation (increase) of Cai in myocytes associated with morphine
1) Confidence 0.14 Published 1991 Journal Life Sci. Section Abstract Doc Link 1847734 Disease Relevance 0 Pain Relevance 1.43
In rat ventricular cardiomyocytes loaded with the fluorescent Ca2+ indicator Indo-1/AM, the delta opioid receptor agonist Leu-Enk caused Cai oscillations and abolished the caffeine-induced Cai transient.
Negative_regulation (abolished) of Positive_regulation (caffeine-induced) of Cai in cardiomyocytes associated with agonist and opioid receptor
2) Confidence 0.04 Published 1991 Journal Boll. Soc. Ital. Biol. Sper. Section Abstract Doc Link 1657046 Disease Relevance 0 Pain Relevance 0.48

General Comments

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