INT129118

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Context Info
Confidence 0.56
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.89
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (NF2) nucleolus (NF2) plasma membrane (NF2)
cytoskeleton (NF2) nucleus (NF2) cytoplasm (NF2)
NF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 77.60 Quite High
palliative 1 70.88 Quite High
imagery 5 42.52 Quite Low
cva 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
hypoalgesia 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 10 100.00 Very High Very High Very High
Neurofibromatosis 2 8 100.00 Very High Very High Very High
Lung Cancer 5 99.18 Very High Very High Very High
Meningioma 65 98.68 Very High Very High Very High
Vascular Malformations 1 95.12 Very High Very High Very High
Malignant Neoplastic Disease 2 89.12 High High
Hamartoma 1 86.68 High High
Dyspnea 1 79.12 Quite High
Angina 1 77.60 Quite High
Pleural Effusion 1 76.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Some studies revealed that loss of 22q12 (NF2 gene) in an each case of meningioangiomatosis and meningioangiomatosis-associated meningioma indicated the possibility of which meningioangiomatosis may be neoplastic in nature [8,19].
Negative_regulation (loss) of NF2 gene associated with neurofibromatosis 2 and meningioma
1) Confidence 0.56 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2904739 Disease Relevance 0.78 Pain Relevance 0
Mesothelioma has an unusual molecular pathology with loss of tumour suppressor genes being the predominant pattern of lesions, especially the P16INK4A, and P14ARF, and NF2 genes, rather than the more common p53 and Rb tumour suppressor genes.
Negative_regulation (loss) of NF2 associated with lung cancer and cancer
2) Confidence 0.41 Published 2005 Journal Lancet Section Abstract Doc Link 16054941 Disease Relevance 1.11 Pain Relevance 0.15

General Comments

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