INT129175

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Context Info
Confidence 0.28
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 3.05
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (PRAM1)
PRAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
TRP channel 4 100.00 Very High Very High Very High
Inflammation 1 89.44 High High
Inflammatory marker 1 81.76 Quite High
Pain 2 25.00 Low Low
nociceptor 1 25.00 Low Low
cva 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dengue Hemorrhagic Fever 67 99.84 Very High Very High Very High
Channelopathies 1 99.34 Very High Very High Very High
Dengue 63 99.24 Very High Very High Very High
Disease 21 99.04 Very High Very High Very High
INFLAMMATION 2 89.44 High High
Targeted Disruption 2 65.12 Quite High
Thrombocytopenia 1 55.84 Quite High
Infection 32 16.00 Low Low
Shock 12 5.00 Very Low Very Low Very Low
Communicable Diseases 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PRAM1 is down-regulated in DSS patients relative to both DHF and DF patients, as is CD14.
Negative_regulation (regulated) of PRAM1 associated with dengue and dengue hemorrhagic fever
1) Confidence 0.28 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2886038 Disease Relevance 2.10 Pain Relevance 0.04
At this point, four channelopathies have been identified in which a defect in a TRP channel-encoding gene is the direct cause of disease.
Negative_regulation (defect) of channel-encoding gene associated with trp channel, disease and channelopathies
2) Confidence 0.02 Published 2005 Journal Sci. STKE Section Abstract Doc Link 16077087 Disease Relevance 0.95 Pain Relevance 0.21

General Comments

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