INT129188

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Context Info
Confidence 0.61
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 0.52
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ATF3) nucleolus (ATF3) nucleus (ATF3)
ATF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 94.68 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 93.96 High High
Colon Cancer 2 91.40 High High
Apoptosis 2 86.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We identified three putative Egr-1 binding sites in the promoter of ATF3 and report for the first time that the molecular mechanism responsible for the transcriptional regulation of ATF3 by two divergent pharmaceutical compounds, sulindac sulfide and troglitazone, involved the early growth response gene-1 (Egr-1).
Regulation (responsible) of Regulation (regulation) of ATF3
1) Confidence 0.61 Published 2005 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 16079301 Disease Relevance 0.25 Pain Relevance 0.08
Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene.
Regulation (involves) of Regulation (regulation) of activating transcription factor 3
2) Confidence 0.27 Published 2005 Journal J. Pharmacol. Exp. Ther. Section Title Doc Link 16079301 Disease Relevance 0.27 Pain Relevance 0.09

General Comments

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