INT129206

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (RYBP, TGFB1) nucleus (RYBP, TGFB1) nucleoplasm (RYBP)
aging (TGFB1) intracellular (RYBP) enzyme binding (TGFB1)
RYBP (Homo sapiens)
TGFB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 11 100.00 Very High Very High Very High
cytokine 3 88.24 High High
Inflammation 4 84.20 Quite High
Inflammatory mediators 1 47.56 Quite Low
chemokine 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 94.64 High High
Hepatotoxicity 5 92.80 High High
INFLAMMATION 5 84.20 Quite High
Stress 3 83.44 Quite High
Necrosis 2 67.52 Quite High
Cancer 1 67.16 Quite High
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As observed with NAC pretreatment, the loss of NF-kappaB p50 was associated with decreased ability of APAP to upregulate TNFalpha, KC/gro, and IL-10 expression and increased expression of IL-4 and TGFbeta.
APAP Positive_regulation (upregulate) of Gene_expression (expression) of TGFbeta associated with paracetamol
1) Confidence 0.00 Published 2006 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 16081117 Disease Relevance 1.04 Pain Relevance 0.95

General Comments

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