INT129227

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Context Info
Confidence 0.14
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 2.54
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (DNASE1) extracellular region (DNASE1) nucleus (DNASE1)
DNASE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 9 99.66 Very High Very High Very High
Angina 2 74.84 Quite High
Inflammation 10 25.28 Quite Low
iatrogenic 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Overdose 5 99.84 Very High Very High Very High
Dyspnea 4 98.96 Very High Very High Very High
Death 18 98.52 Very High Very High Very High
Adhesions 2 97.60 Very High Very High Very High
Stress 1 95.64 Very High Very High Very High
Suppuration 20 95.20 Very High Very High Very High
Infection 53 91.36 High High
Apoptosis 1 88.72 High High
Necrosis 4 87.32 High High
Cancer 13 86.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intrapleural DNase
DNase Binding (Intrapleural) of
1) Confidence 0.14 Published 2010 Journal Clinical Medicine Insights. Circulatory, Respiratory and Pulmonary Medicine Section Body Doc Link PMC2998927 Disease Relevance 0.92 Pain Relevance 0.07
DNase alone appears to be associated with increased frequency of surgery/death.
DNase Binding (associated) of associated with death
2) Confidence 0.13 Published 2010 Journal Clinical Medicine Insights. Circulatory, Respiratory and Pulmonary Medicine Section Body Doc Link PMC2998927 Disease Relevance 0.73 Pain Relevance 0
After the treatment with DNase, the 0.1-2 ?
DNase Binding (treatment) of
3) Confidence 0.08 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2867810 Disease Relevance 0 Pain Relevance 0
Additional processing, such as treating the specimens with DNase, reduced the background signal and increased the percentage of viral reads in some instances (data not shown).
DNase Binding (specimens) of
4) Confidence 0.06 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2290972 Disease Relevance 0.13 Pain Relevance 0
In contrast, nDNA fragmentation after AAP overdose is not caused by caspase-activated DNase but most likely by other intracellular DNase(s), whose activation is dependent on the mitochondrial oxidant stress and peroxynitrite formation.
DNase Spec (likely) Binding (caused) of associated with stress, paracetamol and overdose
5) Confidence 0.05 Published 2005 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 16081675 Disease Relevance 0.76 Pain Relevance 0.47
-actin mRNA, the combination of DNAse and RNAse completely eliminates ?
DNAse Binding (combination) of
6) Confidence 0.03 Published 2007 Journal Virol J Section Body Doc Link PMC1950496 Disease Relevance 0 Pain Relevance 0

General Comments

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