INT129265

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Context Info
Confidence 0.05
First Reported 2003
Last Reported 2006
Negated 3
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.92
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
smooth muscle 2
calponin (Caenorhabditis elegans)
Pain Term Frequency Confidence Heat
cva 1 87.84 High High
Pain 2 55.32 Quite High
palliative 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Cancer 72 98.12 Very High Very High Very High
Necrosis 3 96.24 Very High Very High Very High
Malignant Neoplastic Disease 21 92.24 High High
Carcinoma 17 91.08 High High
Squamous Cell Carcinoma 7 88.56 High High
Hemorrhage 1 87.84 High High
Noninfiltrating Intraductal Carcinoma 10 87.32 High High
Sarcoma 21 87.28 High High
Malignant Fibrous Histiocytoma 3 85.60 High High
Hyperplasia 8 84.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical studies showed weak membranous positivity for epithelial membrane antigen and focal cytoplasmic positivity for CD34; stains for smooth muscle actin, cytokeratin AE1/AE3, desmin, CD56, H-caldesmon, calponin, and S-100 protein were negative.
Neg (negative) Gene_expression (negative) of calponin in smooth muscle
1) Confidence 0.05 Published 2005 Journal Ann Diagn Pathol Section Abstract Doc Link 16084452 Disease Relevance 0.95 Pain Relevance 0.10
In our practice we found use of immunostaining for S100 protein, smooth muscle actin, calponin, cytokeratin 5/6 and cytokeratin 14 to be simple and reliable.
Gene_expression (/) of calponin in smooth muscle
2) Confidence 0.04 Published 2003 Journal Breast Cancer Res Section Body Doc Link PMC314417 Disease Relevance 1.04 Pain Relevance 0
Stains were negative for cytokeratin (AE1/AE3), actin (HHF-35, IA4), calponin, myo-D1, S100 protein, CD34 and CD31.
Neg (negative) Gene_expression (negative) of calponin
3) Confidence 0.03 Published 2006 Journal Int Semin Surg Oncol Section Body Doc Link PMC1538603 Disease Relevance 0.74 Pain Relevance 0
SMA, S-100, calponin, inhibin, Mic-2, desmin and myoglobin were negative in the basaloid islands.
Neg (negative) Gene_expression (negative) of calponin
4) Confidence 0.01 Published 2006 Journal World J Surg Oncol Section Body Doc Link PMC1526432 Disease Relevance 1.20 Pain Relevance 0

General Comments

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