INT129296

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.54
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IKBKE) plasma membrane (IKBKE) nucleus (IKBKE)
cytoplasm (IKBKE)
Anatomy Link Frequency
SH-SY5Y 2
IKBKE (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 8 99.80 Very High Very High Very High
narcan 2 99.44 Very High Very High Very High
Opioid 2 85.36 High High
Kinase C 2 70.80 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 6 99.60 Very High Very High Very High
Bordatella Infection 2 88.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mu-opioid receptor-mediated phosphorylation of IkappaB kinase in human neuroblastoma SH-SY5Y cells.
Phosphorylation (phosphorylation) of IkappaB kinase in SH-SY5Y associated with neuroblastoma, narcan and opioid receptor
1) Confidence 0.35 Published 2005 Journal Neurosignals Section Title Doc Link 16088228 Disease Relevance 0.28 Pain Relevance 0.35
Here we demonstrate that activation of the mu-opioid receptor in human neuroblastoma SH-SY5Y cells led to the phosphorylations of IkappaB kinase (IKK) and p65, denoting the stimulation of the nuclear factor-kappaB (NFkappaB) transcription factor.
Phosphorylation (phosphorylations) of IkappaB kinase in SH-SY5Y associated with neuroblastoma and opioid receptor
2) Confidence 0.35 Published 2005 Journal Neurosignals Section Abstract Doc Link 16088228 Disease Relevance 0.26 Pain Relevance 0.28

General Comments

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