INT129341

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.67
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Nf1) signal transduction (Nf1) nucleus (Nf1)
intracellular (Nf1) extracellular matrix organization (Nf1) protein complex (Nf1)
Nf1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 94.92 High High
qutenza 2 71.92 Quite High
addiction 2 66.32 Quite High
Action potential 2 47.52 Quite Low
Nerve growth factor 1 25.12 Quite Low
cINOD 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Watson Syndrome 10 100.00 Very High Very High Very High
Cancer 117 99.12 Very High Very High Very High
Injury 1 96.64 Very High Very High Very High
Hematologic Neoplasms 2 89.08 High High
Myeloid Leukemia 1 87.36 High High
Apoptosis 41 67.36 Quite High
Leukemia 2 45.96 Quite Low
Glioblastoma 1 38.40 Quite Low
Neurofibroma 1 35.64 Quite Low
Lymphatic System Cancer 7 34.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NF1 results from a heterozygous mutation of the NF1 gene, leading to decreased levels of neurofibromin, the protein product of the NF1 gene.
Negative_regulation (decreased) of Gene_expression (product) of NF1 associated with watson syndrome
1) Confidence 0.43 Published 2005 Journal J. Neurophysiol. Section Abstract Doc Link 16093333 Disease Relevance 0.85 Pain Relevance 0.17
mice, presumably by inactivating Nf1 gene expression as a myeloid lineage tumor suppressor gene.
Negative_regulation (inactivating) of Gene_expression (expression) of Nf1 associated with cancer
2) Confidence 0.33 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1361617 Disease Relevance 0.82 Pain Relevance 0.03

General Comments

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