INT129399

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Context Info
Confidence 0.66
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 3.08
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (SOD1) peroxisome (SOD1) protein complex (SOD1)
cytoplasm (SOD1) cytosol (SOD1) extracellular space (SOD1)
Anatomy Link Frequency
muscle 1
corpus luteum 1
SOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
diclofenac 80 92.68 High High
cva 5 83.20 Quite High
cINOD 11 33.12 Quite Low
COX2 1 25.00 Low Low
endometriosis 42 5.00 Very Low Very Low Very Low
cytokine 23 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
bradykinin 8 5.00 Very Low Very Low Very Low
Migraine 5 5.00 Very Low Very Low Very Low
Dismenorea 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 2 3 89.04 High High
Stress 153 87.92 High High
Parkinson's Disease 6 85.88 High High
Pulmonary Embolism 4 83.20 Quite High
Death 21 82.28 Quite High
Cancer 30 80.64 Quite High
Carcinoma 7 80.40 Quite High
Recurrence 2 79.96 Quite High
Disease 26 79.52 Quite High
Apoptosis 59 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The HO-1, SOD-1, and SOD-2 transcript levels were significantly lower in the cancerous tissue, whereas no significant difference was apparent for both EGFR and HER-2 mRNA levels.
Transcription (levels) of SOD
1) Confidence 0.66 Published 2010 Journal Journal of Nucleic Acids Section Body Doc Link PMC2911612 Disease Relevance 0.99 Pain Relevance 0.04
Furthermore, inhibition of SOD mRNAs expression by EUG was strongly potentiated by the addition of 5 mM N-acetyl cysteine (NAC) or glutathione (GSH), whereas NAC or GSH alone did not affect the expression of SOD mRNAs.
Transcription (expression) of SOD
2) Confidence 0.52 Published 2005 Journal Anticancer Res. Section Abstract Doc Link 16101137 Disease Relevance 0.23 Pain Relevance 0
The HO-1, SOD-1, and SOD-2 transcript levels were significantly lower in the cancerous tissue, whereas no significant difference was apparent for both EGFR and HER-2 mRNA levels.
Transcription (levels) of SOD
3) Confidence 0.49 Published 2010 Journal Journal of Nucleic Acids Section Body Doc Link PMC2911612 Disease Relevance 0.99 Pain Relevance 0.04
For instance, stautosporine, a protein kinase inhibitor, did not affect the mRNA levels of SOD1 and SOD2, but decreased protein and activity levels of both enzymes [48].
Transcription (levels) of SOD1
4) Confidence 0.33 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896885 Disease Relevance 0.30 Pain Relevance 0.16
SOD levels after the isokinetic muscle endurance test were significantly lower in the CoQ10 compared to CON group (p < 0.05).
Transcription (levels) of SOD in muscle
5) Confidence 0.31 Published 2008 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2315638 Disease Relevance 0.25 Pain Relevance 0
However, in the corpus luteum from pregnant patients, the mRNA expression for Cu-Zn superoxide dismutase was significantly higher than that in midcycle corpora lutea.
Transcription (expression) of Cu-Zn superoxide dismutase in corpus luteum
6) Confidence 0.28 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1215514 Disease Relevance 0.23 Pain Relevance 0
superoxide dismutase (SOD) ensures that the latter reaction
Transcription (ensures) of SOD
7) Confidence 0.08 Published 2004 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC555773 Disease Relevance 0.09 Pain Relevance 0

General Comments

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