INT129427

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PPA1) cytoplasm (PPA1)
Anatomy Link Frequency
body 1
PPA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 78.32 Quite High
Analgesic 1 77.20 Quite High
antagonist 1 46.16 Quite Low
dopamine receptor 1 45.72 Quite Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 1 90.96 High High
INFLAMMATION 2 78.32 Quite High
Cancer 1 67.08 Quite High
Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mode of action of these compounds in the 50-100 microM concentration range appeared to be by increasing lipid excretion from the body and by inhibiting rate-limiting enzyme activities for the de novo synthesis of lipids and cholesterol (e.g., phosphatidylate phosphohydrolase, ATP-dependent citrate lyase, cytoplasmic acetyl coenzyme A [CoA] synthetase, HMG CoA reductase, and acetyl CoA carboxylase).
Transcription (synthesis) of phosphohydrolase in body
1) Confidence 0.00 Published 2005 Journal Curr. Med. Chem. Section Abstract Doc Link 16101500 Disease Relevance 0.24 Pain Relevance 0.12

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox