INT129448

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Context Info
Confidence 0.27
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Stat6) nucleolus (Stat6) nucleus (Stat6)
DNA binding (Stat6) cytoplasm (Stat6) signal transducer activity (Stat6)
Anatomy Link Frequency
2B7 1
Stat6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 3 100.00 Very High Very High Very High
Morphine 5 98.76 Very High Very High Very High
Cancer pain 1 96.60 Very High Very High Very High
Analgesic 1 94.80 High High
Opioid 1 94.08 High High
Disease Link Frequency Relevance Heat
Cancer Pain 1 96.60 Very High Very High Very High
Cancer 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study evaluated genetic variation in the mu-opioid receptor, betaarrestin2, stat6 and uridine diphosphate-glucuronysltransferase 2B7 (UGT2B7) genes, in patients who responded to morphine vs those who were switched to alternative opioids.
Positive_regulation (variation) of stat6 in 2B7 associated with opioid receptor, opioid and morphine
1) Confidence 0.27 Published 2005 Journal Pharmacogenomics J. Section Abstract Doc Link 16103897 Disease Relevance 0.17 Pain Relevance 0.70

General Comments

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