INT129470

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Context Info
Confidence 0.22
First Reported 2005
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.36
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RRM2) nucleoplasm (RRM2) small molecule metabolic process (RRM2)
oxidoreductase activity (RRM2) cytoplasm (RRM2)
RRM2 (Homo sapiens)
Pain Link Frequency Relevance Heat
isoflurane 3 66.52 Quite High
anesthesia 19 60.88 Quite High
qutenza 1 10.00 Low Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eczema 32 90.04 High High
Toothache 2 67.48 Quite High
Sunburn 1 61.24 Quite High
Disease 26 5.00 Very Low Very Low Very Low
Cardiovascular Disease 12 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 10 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 8 5.00 Very Low Very Low Very Low
Disease Susceptibility 4 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Sleep Disorders 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There were no differences in BR (R2 or R3) between the painful and nonpainful sides (P > .569), and the BR (R2 and R3) was not significantly modulated by experimental pain (P > .080).
Neg (not) Regulation (modulated) of R2
1) Confidence 0.22 Published 2005 Journal J Orofac Pain Section Body Doc Link 16106718 Disease Relevance 0.07 Pain Relevance 0
These correlation coefficients suggest that only between 0.14 and 0.22 of the variance (r2) is accounted for by the differences in level of practise.
Regulation (accounted) of r2
2) Confidence 0.19 Published 2006 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1697735 Disease Relevance 0.29 Pain Relevance 0
The SNPassoc R package [103] was then used to measure LD by calculating r2 between the set of SNP genotypes and the copy number alleles.
Regulation (calculating) of r2
3) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2747275 Disease Relevance 0 Pain Relevance 0
The median of the maximum r2 values for single SNPs located up to 100 kb around the boundaries of each CNV was 0.37, indicating a low overall disequilibrium between SNPs and copy number alleles.
Regulation (values) of r2
4) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2747275 Disease Relevance 0 Pain Relevance 0
The ratios of R1, crossed R1 and R2 responses obtained in Protocols 1 and 2 were calculated and the latencies of each response were averaged.
Regulation (responses) of R2
5) Confidence 0.03 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2703761 Disease Relevance 0 Pain Relevance 0.27

General Comments

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