INT129590

Context Info Confidence 0.61 First Reported 2005 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 4 Total Number 4 Disease Relevance 0.67 Pain Relevance 1.03

unfolded protein binding (St13) protein folding (St13) cytosol (St13) protein complex (St13) cytoplasm (St13)

Anatomy Link Frequency pancreas 2 Primary neuron 1 ventral 1 St13 (Mus musculus)

Pain Link Frequency Relevance Heat Ventral tegmentum 9 100.00 Substantia nigra 6 100.00 monoamine 6 99.78 Catecholamine 1 90.64 agonist 58 85.40 Paracetamol 6 75.00 Dopamine 5 75.00 Serotonin 4 75.00 IPN 8 69.28 midbrain 3 67.52

Disease Link Frequency Relevance Heat Liver Cancer 2 91.36 Injury 2 75.00 Inflammatory Pain 8 69.28 Targeted Disruption 15 69.20 Severe Combined Immunodeficiency 2 63.36 Pain 15 42.32 Overdose 2 25.00 Necrosis 2 25.00 Hepatitis 2 25.00 Cancer 2 25.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Human hepatocarcinoma-intestine-pancreas/pancreatic-associated protein HIP/PAP is a secreted C-type lectin belonging to group VII, according to Drickamer's classification.

Localization (secreted) of HIP/PAP in pancreas

1) Confidence 0.61 Published 2005 Journal Hepatology Section Abstract Doc Link 16116631 Disease Relevance 0.30 Pain Relevance 0.07

Human hepatocarcinoma-intestine-pancreas/pancreatic-associated protein HIP/PAP is a secreted C-type lectin belonging to group VII, according to Drickamer's classification.

Localization (secreted) of HIP/PAP in pancreas

2) Confidence 0.57 Published 2005 Journal Hepatology Section Abstract Doc Link 16116631 Disease Relevance 0.30 Pain Relevance 0.07

In the present report, fast-scan cyclic voltammetry was used to identify the monoamines that were released by electrical stimulation in mouse brain slices containing ventral tegmental area (VTA), substantia nigra (SN) -pars compacta (SNc) and -pars reticulata (SNr).

Localization (released) of SNc in ventral associated with ventral tegmentum, substantia nigra and monoamine

3) Confidence 0.22 Published 2006 Journal J. Neurochem. Section Abstract Doc Link 16300629 Disease Relevance 0 Pain Relevance 0.73

Primary neuron cultures were acutely treated with SNC80 (10 nM, 100 nM, 1 µM), or ARM390 (100 nM, 1 µM, 10 µM).

Localization (treated) of SNC80 in Primary neuron

4) Confidence 0.09 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2672171 Disease Relevance 0.07 Pain Relevance 0.15

General Comments

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