INT129592

Context Info Confidence 0.26 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.84 Pain Relevance 0.16

cytoplasm (St13, Stat3) unfolded protein binding (St13) DNA binding (Stat3) protein complex (St13) signal transducer activity (Stat3) cell proliferation (Stat3)

Anatomy Link Frequency liver 2 St13 (Mus musculus) Stat3 (Mus musculus)

Pain Link Frequency Relevance Heat Paracetamol 3 82.40

Disease Link Frequency Relevance Heat Cancer 1 99.80 Targeted Disruption 4 99.58 Necrosis 1 99.56 Severe Combined Immunodeficiency 1 84.48 Hepatitis 1 79.84 Injury 1 75.00 Liver Cancer 1 69.80 Overdose 1 47.20 Liver Failure 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Comparison of the early events posthepatectomy in control and transgenic mice indicated that HIP/PAP accelerates the accumulation/degradation of nuclear phospho-signal transducer activator transcription factor 3 and tumor necrosis factor alpha level, thus reflecting that HIP/PAP accelerates liver regeneration.

HIP/PAP Positive_regulation (accelerates) of Protein_catabolism (accumulation/degradation) of nuclear phospho-signal transducer activator transcription factor 3 in liver associated with targeted disruption, necrosis and cancer

1) Confidence 0.26 Published 2005 Journal Hepatology Section Abstract Doc Link 16116631 Disease Relevance 0.84 Pain Relevance 0.16

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