INT129632

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sod1) aging (Sod1) peroxisome (Sod1)
intracellular (Sod1) protein complex (Sod1) cytoplasm (Sod1)
Sod1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 1 98.36 Very High Very High Very High
COX2 1 92.96 High High
Spinal cord 1 74.84 Quite High
agonist 2 64.80 Quite High
cINOD 1 58.96 Quite High
Inflammation 2 52.64 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 4 100.00 Very High Very High Very High
Motor Neuron Diseases 4 75.00 Quite High
Disease 1 69.88 Quite High
Body Weight 1 68.72 Quite High
INFLAMMATION 3 58.72 Quite High
Death 1 47.08 Quite Low
Neurodegenerative Disease 1 45.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, mRNA levels of the suppressor of cytokine signaling 1 and 3 genes were increased by Pio, whereas both the mRNA and protein levels of endogenous mouse SOD1 and of transgenic human SOD1 remained unaffected.
Neg (unaffected) Negative_regulation (unaffected) of Transcription (levels) of SOD1 associated with targeted disruption and cytokine
1) Confidence 0.43 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 16120782 Disease Relevance 0.69 Pain Relevance 0.28

General Comments

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