INT129680

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Context Info
Confidence 0.53
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.68
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hsf1) DNA binding (Hsf1) protein complex (Hsf1)
response to stress (Hsf1) cytoplasm (Hsf1)
Hsf1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 96.96 Very High Very High Very High
ischemia 3 75.00 Quite High
qutenza 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fever 8 98.88 Very High Very High Very High
Myeloid Leukemia 24 90.44 High High
Chronic Myeloid Leukemia 16 84.96 Quite High
Apoptosis 16 82.32 Quite High
Shock 17 75.00 Quite High
Reperfusion Injury 2 75.00 Quite High
Cv Unclassified Under Development 2 75.00 Quite High
Stress 23 70.52 Quite High
Cancer 10 69.60 Quite High
Aging 2 50.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
WBH preconditioning resulted in 2.7-fold and 3.4-fold increase in cardiac HSF1 mRNA and protein expression respectively 2 hours after WBH, which was inhibited in the siRNA-treated mice.
Transcription (expression) of HSF1 associated with fever
1) Confidence 0.53 Published 2005 Journal J. Mol. Cell. Cardiol. Section Abstract Doc Link 16125197 Disease Relevance 1.03 Pain Relevance 0.17
Resveratrol was found to modulate the function of HSF1 as a transcription factor for Hsp70 in K562 cells [11].
Transcription (transcription) of HSF1
2) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2806839 Disease Relevance 0.51 Pain Relevance 0
This brings down the transcriptional activity of HSF1 and Hsp70 production in K562 cells.
Transcription (activity) of HSF1
3) Confidence 0.20 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2806839 Disease Relevance 0.15 Pain Relevance 0

General Comments

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