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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.78

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Pain Term Frequency Confidence Heat
diclofenac 2 97.66 Very High Very High Very High
aspirin 2 96.80 Very High Very High Very High
cINOD 8 96.26 Very High Very High Very High
Inflammation 1 81.60 Quite High
Disease Term Frequency Confidence Heat
Alzheimer's Dementia 3 100.00 Very High Very High Very High
Disease 5 87.24 High High
INFLAMMATION 3 83.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we used fluorescence spectroscopy with thioflavin T and electron microscopy to examine the effects of NSAIDs such as ibuprofen, aspirin, meclofenamic acid sodium salt, diclofenac sodium salt, ketoprofen, flurbiprofen, naproxen, sulindac sulfide and indomethacin on the formation, extension, and destabilization of beta-amyloid fibrils (fA beta) at pH 7.5 at 37 degrees C in vitro.
Negative_regulation (destabilization) of beta-amyloid fibrils associated with aspirin, alzheimer's dementia, cinod and diclofenac
1) Confidence 0.42 Published 2005 Journal Neuropharmacology Section Abstract Doc Link 16125740 Disease Relevance 0.82 Pain Relevance 0.78

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