INT129721

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Context Info
Confidence 0.51
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.75
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFRSF10D)
TNFRSF10D (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 91.64 High High
Chronic pancreatitis 13 87.76 High High
cytokine 1 67.60 Quite High
fibrosis 5 61.44 Quite High
cINOD 1 50.00 Quite Low
Disease Link Frequency Relevance Heat
Death 8 98.92 Very High Very High Very High
Apoptosis 11 97.20 Very High Very High Very High
Necrosis 1 92.88 High High
Cancer 1 92.52 High High
INFLAMMATION 1 91.64 High High
Pancreatitis 13 87.76 High High
Fibrosis 6 87.40 High High
Hypoglycemia 2 87.12 High High
Keloid Scars 1 86.72 High High
Colon Cancer 2 77.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, islets are strongly induced for TRAIL-receptor(R)-4 lacking a functional death domain.
Positive_regulation (induced) of TRAIL-receptor associated with death
1) Confidence 0.51 Published 2006 Journal Verh Dtsch Ges Pathol Section Abstract Doc Link 17867593 Disease Relevance 1.25 Pain Relevance 0.49
IND (0.1 mmol/L for 1 h) significantly up-regulated pro-apoptotic genes in four families: (1) TNF receptor and ligand, (2) Caspase, (3) Bcl-2 and (4) Caspase recruiting domain.
Positive_regulation (up-regulated) of TNF receptor
2) Confidence 0.17 Published 2006 Journal World J. Gastroenterol. Section Body Doc Link 17072976 Disease Relevance 0.23 Pain Relevance 0
However, islets are strongly induced for TRAIL-receptor (R)-4 lacking the functional death domain.
Positive_regulation (induced) of TRAIL-receptor associated with death
3) Confidence 0.06 Published 2005 Journal Lab. Invest. Section Abstract Doc Link 16127431 Disease Relevance 1.27 Pain Relevance 0.41

General Comments

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