INT129756

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Context Info
Confidence 0.34
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 6.45
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MUC5AC) cell adhesion (MUC5AC)
Anatomy Link Frequency
tears 1
MUC5AC (Homo sapiens)
Pain Link Frequency Relevance Heat
ketamine 2 100.00 Very High Very High Very High
Analgesic 1 100.00 Very High Very High Very High
Inflammatory response 3 97.80 Very High Very High Very High
metalloproteinase 40 92.12 High High
Inflammation 20 92.08 High High
anesthesia 5 84.32 Quite High
isoflurane 1 83.72 Quite High
Central nervous system 14 55.80 Quite High
adenocard 7 50.00 Quite Low
headache 3 16.32 Low Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 165 100.00 Very High Very High Very High
Infection 54 100.00 Very High Very High Very High
Pancreatic Cancer 56 99.36 Very High Very High Very High
Sjoegrens Syndrome 31 99.04 Very High Very High Very High
INFLAMMATION 23 97.40 Very High Very High Very High
Heart Defects 1 96.64 Very High Very High Very High
Meningitis 77 92.04 High High
Neurological Disease 14 91.64 High High
Cancer 58 90.72 High High
Syndrome 49 90.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CSF was collected from patients who were suspected of having TBM or other infections before they received any treatment.
Regulation (infections) of TBM associated with mycobacterial infection and infection
1) Confidence 0.34 Published 2004 Journal BMC Neurol Section Body Doc Link PMC529262 Disease Relevance 1.28 Pain Relevance 0
sabA (BabA+) mutant bound fucosylated, secretor-dependent ABH/Leb antigens (but not the shorter Lea or sialylated antigens), whereas the ?
Regulation (dependent) of Leb
2) Confidence 0.20 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2174967 Disease Relevance 0.71 Pain Relevance 0.13
Then, to examine the function of MUC5AC in pancreatic cancer cells, we delivered siRNA vector targeting MUC5AC into two human pancreatic cancer cells SW1990 and BxPC3 which were expressed MUC5AC.
Regulation (targeting) of MUC5AC associated with pancreatic cancer
3) Confidence 0.19 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2893453 Disease Relevance 0.43 Pain Relevance 0
Furthermore, production of VEGF and phosphorylation of VEGFR-1 were significantly reduced by MUC5AC down regulation.
Regulation (regulation) of MUC5AC
4) Confidence 0.19 Published 2010 Journal J Exp Clin Cancer Res Section Abstract Doc Link PMC2893453 Disease Relevance 0.96 Pain Relevance 0.09
One study by Zhao et al. [46] found no difference in MUC5AC levels in the tears of KCS subjects versus normals.
Neg (no) Regulation (difference) of MUC5AC in tears associated with sjoegrens syndrome
5) Confidence 0.15 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2927371 Disease Relevance 1.09 Pain Relevance 0
Sensitivity in the TBM group was 96% (96% of the culture positive samples were above the cut-off value) whereas it was only 78% in the clinically suspected group.
Regulation (Sensitivity) of TBM associated with mycobacterial infection
6) Confidence 0.09 Published 2006 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1448186 Disease Relevance 1.79 Pain Relevance 0.03
Effects of ketamine on serum and tracheobronchial aspirate interleukin-6 levels in infants undergoing cardiac surgery.
Regulation (Effects) of tracheobronchial aspirate associated with ketamine and analgesic
7) Confidence 0.00 Published 2005 Journal J. Cardiothorac. Vasc. Anesth. Section Title Doc Link 16130059 Disease Relevance 0.19 Pain Relevance 0.45

General Comments

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