INT129801

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Clec7a)
Clec7a (Mus musculus)
Pain Link Frequency Relevance Heat
spinal inflammation 12 50.00 Quite Low
rheumatoid arthritis 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 9 78.36 Quite High
Low Back Pain 12 76.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: The expression of GR beta mRNA, which is a dominant negative regulator for the glucocorticoid response, was increased in AS patients.
Positive_regulation (increased) of Gene_expression (expression) of GR beta mRNA
1) Confidence 0.04 Published 2005 Journal Korean J. Intern. Med. Section Body Doc Link 16134770 Disease Relevance 0.12 Pain Relevance 0
The results suggest that the increased expression of GR beta mRNA may be related to the ineffectiveness of glucocorticoids for the treatment of AS.


Positive_regulation (increased) of Gene_expression (expression) of GR beta mRNA
2) Confidence 0.04 Published 2005 Journal Korean J. Intern. Med. Section Body Doc Link 16134770 Disease Relevance 0.10 Pain Relevance 0
GR beta mRNA expression of the AS patients (2.02 [range: 0.99-7.21], median [25th-75th percentiles]) was enhanced compared with that of the controls (0.78 [range: 0.43-1.62]) and the RA patients (0.98 [range: 0.79-1.18]).
Positive_regulation (enhanced) of Gene_expression (expression) of GR beta mRNA
3) Confidence 0.04 Published 2005 Journal Korean J. Intern. Med. Section Body Doc Link 16134770 Disease Relevance 0.15 Pain Relevance 0

General Comments

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