INT129802

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Context Info
Confidence 0.13
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Clec7a)
Clec7a (Mus musculus)
Pain Link Frequency Relevance Heat
spinal inflammation 16 50.00 Quite Low
cytokine 9 28.68 Quite Low
rheumatoid arthritis 12 5.00 Very Low Very Low Very Low
tolerance 9 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 12 78.36 Quite High
Low Back Pain 16 76.60 Quite High
Metastasis 46 50.00 Quite Low
Leukemia 1 40.44 Quite Low
Cancer 81 17.80 Low Low
Skin Cancer 8 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Experimental Melanoma 5 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Shock 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The pSilencer 1.0 U6 vector, expressing small hairpin RNA (shRNA) against TLR2, TLR6 or Dectin-1, was constructed.
Gene_expression (expressing) of Dectin-1
1) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716531 Disease Relevance 0 Pain Relevance 0
The results suggest that the increased expression of GR beta mRNA may be related to the ineffectiveness of glucocorticoids for the treatment of AS.


Gene_expression (expression) of GR beta mRNA
2) Confidence 0.05 Published 2005 Journal Korean J. Intern. Med. Section Body Doc Link 16134770 Disease Relevance 0.10 Pain Relevance 0
CONCLUSION: The expression of GR beta mRNA, which is a dominant negative regulator for the glucocorticoid response, was increased in AS patients.
Gene_expression (expression) of GR beta mRNA
3) Confidence 0.05 Published 2005 Journal Korean J. Intern. Med. Section Body Doc Link 16134770 Disease Relevance 0.12 Pain Relevance 0
GR beta mRNA expression of the AS patients (2.02 [range: 0.99-7.21], median [25th-75th percentiles]) was enhanced compared with that of the controls (0.78 [range: 0.43-1.62]) and the RA patients (0.98 [range: 0.79-1.18]).
Gene_expression (expression) of GR beta mRNA
4) Confidence 0.05 Published 2005 Journal Korean J. Intern. Med. Section Body Doc Link 16134770 Disease Relevance 0.15 Pain Relevance 0
The level of GR beta mRNA expression was not related to the inflammatory markers or the disease activity score 28 for the RA patients, and it was not related to the Bath ankylosing spondylitis disease activity index for the AS patients.
Gene_expression (expression) of GR beta mRNA
5) Confidence 0.05 Published 2005 Journal Korean J. Intern. Med. Section Body Doc Link 16134770 Disease Relevance 0.14 Pain Relevance 0

General Comments

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