INT129852

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.56
First Reported 2005
Last Reported 2005
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFRSF11A) cell death (OLR1) extracellular region (OLR1)
cell adhesion (OLR1) plasma membrane (OLR1) cell-cell signaling (TNFRSF11A)
Anatomy Link Frequency
monocytes 4
OLR1 (Homo sapiens)
TNFRSF11A (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 6 50.00 Quite Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 6 69.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: The data suggest that the activation of NF-kB in monocytes of UA patients is, at least in part, induced by circulating molecules such as ox-LDL, which has been found to be particularly elevated in UA patients.


ox-LDL Positive_regulation (induced) of Positive_regulation (activation) of NF-kB in monocytes
1) Confidence 0.56 Published 2005 Journal J. Am. Coll. Cardiol. Section Body Doc Link 16139128 Disease Relevance 0.10 Pain Relevance 0
In the in vitro studies, ox-LDL dose-dependently increased the activation of NF-kB in monocytes, but not in lymphocytes derived from healthy volunteers.
ox-LDL Neg (not) Positive_regulation (increased) of Positive_regulation (activation) of NF-kB in monocytes
2) Confidence 0.49 Published 2005 Journal J. Am. Coll. Cardiol. Section Body Doc Link 16139128 Disease Relevance 0.14 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox