INT129874

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Context Info
Confidence 0.42
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.45
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CST3, CTSS) lysosome (CST3, CTSS) peptidase activity (CTSS)
extracellular space (CST3) endoplasmic reticulum (CST3) cytoplasm (CST3)
CST3 (Homo sapiens)
CTSS (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 4 46.80 Quite Low
Disease Link Frequency Relevance Heat
Atherosclerosis 16 100.00 Very High Very High Very High
Diabetes Mellitus 16 98.52 Very High Very High Very High
Pathologic Constriction 4 82.96 Quite High
Nicotine Addiction 6 58.32 Quite High
Myocardial Infarction 2 49.52 Quite Low
Cv General 3 Under Development 4 46.80 Quite Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have demonstrated enhanced elastolytic cathepsin S in human atherosclerotic lesions but insufficient amounts of its endogenous inhibitor cystatin C, suggesting alterations of serum cathepsin S and/or cystatin C in patients with atherosclerosis or diabetes.
cystatin C Binding (alterations) of cathepsin S associated with diabetes mellitus and atherosclerosis
1) Confidence 0.42 Published 2006 Journal Atherosclerosis Section Abstract Doc Link 16140306 Disease Relevance 1.24 Pain Relevance 0
We have demonstrated enhanced elastolytic cathepsin S in human atherosclerotic lesions but insufficient amounts of its endogenous inhibitor cystatin C, suggesting alterations of serum cathepsin S and/or cystatin C in patients with atherosclerosis or diabetes.
cystatin C Binding (alterations) of cathepsin S associated with diabetes mellitus and atherosclerosis
2) Confidence 0.42 Published 2006 Journal Atherosclerosis Section Abstract Doc Link 16140306 Disease Relevance 1.21 Pain Relevance 0

General Comments

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