INT129912

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2) helicase activity (Skiv2l)
enzyme binding (PTGS2) protein complex (PTGS2) cytoplasm (PTGS2)
Skiv2l (Mus musculus)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 99.92 Very High Very High Very High
Osteoarthritis 1 93.52 High High
Inflammation 5 92.28 High High
cytokine 1 86.32 High High
Pain 1 85.04 High High
Analgesic 1 75.96 Quite High
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 7 99.52 Very High Very High Very High
Osteoarthritis 1 93.52 High High
Necrosis 1 88.40 High High
Cancer 1 88.04 High High
Pain 1 85.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SKI306X did inhibit the expression of cyclooxygenase-2 (COX-2) enzyme without affecting COX-1 and COX-2 activity.
SKI306X Negative_regulation (inhibit) of Gene_expression (expression) of cyclooxygenase-2
1) Confidence 0.00 Published 2005 Journal Biol. Pharm. Bull. Section Abstract Doc Link 16141526 Disease Relevance 0.87 Pain Relevance 0.54

General Comments

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