INT129919

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SLC6A4) endosome (SLC6A4) extracellular space (IFNA2)
extracellular region (IFNA2) plasma membrane (SLC6A4) cell-cell signaling (IFNA2)
IFNA2 (Homo sapiens)
SLC6A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 9 100.00 Very High Very High Very High
depression 14 96.20 Very High Very High Very High
cytokine 5 79.56 Quite High
monoamine 3 78.60 Quite High
Neurotransmitter 1 60.44 Quite High
Analgesic 1 26.20 Quite Low
alcohol 3 25.00 Low Low
addiction 2 25.00 Low Low
analgesia 1 25.00 Low Low
antidepressant 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Depression 18 96.20 Very High Very High Very High
Hepatitis C Virus Infection 8 75.00 Quite High
Depressive Disorder 1 42.08 Quite Low
Affective Disorder 3 25.00 Low Low
Infection 3 25.00 Low Low
Hepatitis 2 25.00 Low Low
Alcohol Addiction 2 25.00 Low Low
Dementia 1 25.00 Low Low
Catatonia 1 25.00 Low Low
Cognitive Disorder 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Many studies support the serotonin-transporter hypothesis: in vitro, both IFNalpha and interleukine 4 (IL-4) increases the expression of serotonin transporter gene, IFNalpha increases in the production of IL-4 by mononucleus cells (not found in vivo).
IFNalpha Positive_regulation (increases) of Gene_expression (expression) of serotonin transporter gene associated with serotonin
1) Confidence 0.02 Published 2005 Journal Encephale Section Abstract Doc Link 16142050 Disease Relevance 0.38 Pain Relevance 0.69

General Comments

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